Biosafety develops, updates and implements a comprehensive biological safety program including Institutional biosafety policies, guidelines and procedures. Biosafety identifies biological hazards in UCI campus, mainly associated with biological research, suggests methods to mitigate associated risks and serves as a resource for Federal, State and Local regulations and safety guidelines.

BBP-ATD Exposure Control Plan (ECP)

Biomedical Waste Disposal

Biosafety Inspection Checklist

Biosafety Levels (BSL1/BSL2/BSL3)

Biosafety Manual

Pathogen Safety Data Sheets

Permissible Select Toxins

Risk Groups

SOP Templates


Our Programs

  • Institutional Biosafety Committee (IBC)
  • Cal/OSHA Bloodborne Pathogens (BBP)
  • Cal/OSHA Aerosol Transmissible Diseases (ATD)
  • High Containment Laboratory Program


Our Services

  • BUA/IBC application Prereview
  • Biosafety site assessments (BSL2 and BSL3) and consultations
  • Research specific training: Hazard identification, risk management and infectious agent specific discussion
  • SOP development
  • Exposure Control Plan development
  • Biological research-related incident investigations and response
  • Preparing CDC and USDA import/ transport permit application
  • Preparing for CDC and USDA inspection
  • Lab certification for NIH or other grantors
  • ATCC BSL2 upgrade approval



For all BSL2 and higher work, BSCs must be certified annually. Please contact TSS at 1-800-877-7742 to certify your BSC. The lab will be charged by TSS for the certification.

Please contact TSS at 1-800-877-7742 to decontaminate the BSC. After decontamination, submit an EH&S clearance request form.

Please contact your EH&S Coordinator to obtain a biological spill kit.

Biosafety provides consultation on how to set up BSL2 and higher containment labs. Please contact

UCI follows the containment requirements included in the CDC Biosafety in Microbiological and Biomedical Laboratories (BMBL, 5th edition) and NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules. Please check UCI Biosafety Manual for additional information.

Established human cells lines fall under Cal/OSHA Bloodborne Pathogen (BBP) standard. Other examples are: human blood, tissues and organs, non-human primate cell lines, Lentivirus, Hepatitis B virus. As per the standard annual BBP training (via UCLC) and annual review of BBP-ECP is required.

Adenovirus is an aerosol transmissible pathogen under Cal/OSHA Aerosol Transmissible Disease (ATD) standard. Other examples are Herpes Simplex Virus, Influenza virus, Streptococcus spp. (Group A), SARS-Coronavirus. As per the standard annual ATD training (via UCLC) and annual review of ATD-ECP is required.

Please visit the EH&S SOP Library to obtain an SOP template.

Please submit an IBC application. Once an IBC application is submitted, Biosafety will carry out a prereview of the application and provide guidance on the containment levels.

Bunsen burners are not allowed inside the BSC. IBC’s position on Bunsen burners. Contact to obtain a on-demand burner.

Please follow this guidance document. You can obtain the filter by contacting us at